Is Corynebacterium diphtheriae hemolytic?
Corynebacterium Infections☆ Corynebacterium diphtheriae is the etiologic agent of human respiratory and cutaneous diphtheria. There are 3 biotypes (mitis, gravis, and intermedius) of C. diphtheriae, each differentiated by hemolysis, colonial morphology, and fermentative reactions.
What are the signs and symptoms of Corynebacterium diphtheriae?
Signs and symptoms may include:
- A thick, gray membrane covering the throat and tonsils.
- A sore throat and hoarseness.
- Swollen glands (enlarged lymph nodes) in the neck.
- Difficulty breathing or rapid breathing.
- Nasal discharge.
- Fever and chills.
- Tiredness.
What type of hemolysis is Corynebacterium diphtheriae?
CORYNEBACTERIA – CULTIVATION ON BLOOD AGAR on media with blood with a weak beta-hemolysis (C. diphtheriae biotype mitis and gravis) or is nonhemolytic (biotype intermedius).
Does diphtheria cause bleeding?
The characteristic thick membrane of diphtheria infection in the posterior pharynx. Removal of the membrane reveals a bleeding, edematous mucosa.
What does C. diphtheriae cause?
Diphtheria is a serious infection caused by strains of bacteria called Corynebacterium diphtheriae that make toxin (poison). It can lead to difficulty breathing, heart failure, paralysis, and even death. CDC recommends vaccines for infants, children, teens, and adults to prevent diphtheria.
What are the complications of diphtheria?
Complications
- Airway blockage.
- Damage to the heart muscle (myocarditis)
- Nerve damage (polyneuropathy)
- Loss of the ability to move (paralysis)
- Kidney failure.
What does Corynebacterium diphtheriae cause?
What are the virulence factors of C. diphtheriae?
Toxin. The main virulence factor of C. diphtheriae is diphtheria toxin (DT), an exotoxin, released by the bacteria after entering the human body. DT is classified as an AB toxin because it has two components, one for activation and one for binding.
How does the body react to diphtheria?
Damage Response Framework Fever, sore throat, and nasal discharge will develop first with an occasional loss of appetite. The lymph nodes in the neck region will continue to swell due to the infection.
How does diphtheria affect the kidneys?
Kidney damage: The diphtheria toxin may damage the kidneys, affecting their ability to filter wastes from the blood. Nerve damage: The toxin can also cause nerve damage, targeting certain nerves such as those to the throat, making swallowing difficult.
What body system does diphtheria affect?
Diphtheria can infect the respiratory tract (parts of the body involved in breathing) and skin.
What body systems are affected by diphtheria?
Diphtheria can infect the respiratory tract (parts of the body involved in breathing) and skin. In the respiratory tract, it causes a thick, gray coating to build up in the throat or nose. This coating can make it hard to breathe and swallow. Diphtheria skin infections can cause open sores or shallow ulcers.
What are complications of diphtheria?
Which part of the body is affected by diphtheria?
The symptoms of diphtheria include suffocation, swollen lymph nodes in the neck, chills, fever, loud cough, bluish skin, difficulty in breathing, etc. The bacteria live in the mouth, throat, and nose of an infected person and can be passed to others by coughing or sneezing. So, the correct answer is option B.
Why does your throat turn black?
The bacteria most commonly infect your nose and throat. The throat infection causes a gray to black, tough, fiber-like covering, which can block your airways. In some cases, diphtheria infects your skin first and causes skin lesions. Once you are infected, the bacteria make dangerous substances called toxins.