What is Apo olanzapine ODT?
Olanzapine belongs to a group of medicines called antipsychotics. It helps to correct chemical imbalances in the brain, which may cause mental illness. It is used: to treat symptoms of schizophrenia and related psychoses.
What is the brand-name for the drug olanzapine?
Olanzapine oral tablet is available as brand-name drugs and generic drugs. Brand names: Zyprexa, Zyprexa Zydis. Olanzapine comes as a regular tablet and a disintegrating tablet.
What is the difference between olanzapine and olanzapine ODT?
Oral olanzapine is available in the form of ODTs and standard oral tablets (SOT). The ODT formulation of olanzapine is designed to dissolve upon contact with saliva and cannot be easily spat out,8 and may be preferable for patients who are reluctant or unable to swallow tablets.
Is Zyprexa Zydis ODT?
OLANZAPINE ODT (Generic for ZYPREXA ZYDIS) OLANZAPINE/Zyprexa Zydis (oh LAN za peen) is used to treat schizophrenia, psychotic disorders, and bipolar disorder. Bipolar disorder is also known as manic-depression.
What does ODT mean in pharmacy?
This guidance provides pharmaceutical manufacturers of new and generic drug products with an Agency perspective on the definition of an orally disintegrating tablet (ODT)—which is a different dosage form than, for example, a chewable tablet or a tablet that should be swallowed whole with liquid—and also provides …
Is olanzapine used for sleep?
Olanzapine seems to preserve the normal structure of sleep and increase the amount of slow-wave sleep, which might be of additional benefit in treatment of schizophrenia. The effective clinical dose may be lower for females than males.
Is olanzapine a generic name?
Oct. 25, 2011 — The FDA has approved the first generic versions of the drugs Zyprexa and Zyprexa Zydis for the treatment of schizophrenia and bipolar disorder. The brand-name drugs are now made by Eli Lilly & Co. The generic name for the two drugs is olanzapine.
What is the difference between Zyprexa and Zyprexa Zydis?
Zyprexa Zydis wafers are bioequivalent to Zyprexa coated tablets, with a similar rate and extent of absorption. Zyprexa Zydis wafers have the same dosage and frequency of administration as Zyprexa coated tablets. Zyprexa Zydis wafers may be used as an alternative to Zyprexa coated tablets.
Does olanzapine ODT cause weight gain?
Abstract. Olanzapine has frequently been reported to induce substantial weight gain, which is associated with an increased prevalence of dyslipidemia and type 2 diabetes.
Is olanzapine a sublingual ODT?
Olanzapine (OLZ) is a second-generation antipsychotic agent available in 2 solid oral dosage forms, a standard oral tablet (SOT) and an orally disintegrating tablet (ODT). This study assessed the absorption of each by different routes of administration.
What is the difference between Zyprexa and zydis?
What medications contain ODT?
This process has been used to manufacture commercial ODTs for many drugs including desloratadine, lorazepam, piroxicam, loperamide, loratadine, enalapril, clonazepam, rizatriptan, domperidone, famotidine, chlorpheniramine maleate, scopolamine HBr, oxazepam, ondansetron, olanzapine, and selegiline (8, 16, 17, 29).
Is Zyprexa Zydis generic?
What are the side effects of olanzapine ODT?
Drowsiness, dizziness, lightheadedness, stomach upset, dry mouth, constipation, increased appetite, or weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Dizziness and lightheadedness can increase the risk of falling.
Can you swallow olanzapine ODT tablets?
These film coated tablets should be swallowed whole with a glass of water. Olanzapine AN ODT: These orally disintegrating tablets will dissolve in your mouth, therefore do not require water.
How do you administer olanzapine ODT?
The orally disintegrating olanzapine tablet is placed into your mouth and begins dissolving within seconds. Once dissolved, it can be swallowed with or without liquid. Because the orally disintegrating tablets break easily, they should be handled carefully with dry hands.
What does ODT mean on a prescription?
Orally disintegrating tablets (ODTs) provide an alternative to overcome these challenges. They resemble a traditional tablet, but have one important difference: they disintegrate rapidly in the mouth, and therefore do not need to be swallowed.
What is olanzapine ODT used for?
Brand name: Olanzapine ODT (Apo) TM. What it is used for. – Treatment of schizophrenia and related psychoses;. – Short-term treatment, alone or in combination with lithium or valproate, of acute manic episodes associated with bipolar I disorder;. – Preventing recurrence of manic, mixed or depressive episodes in bipolar I disorder.
How do you take olanzapine ODT orally disintegrating tablets?
Olanzapine ODT orally disintegrating tablets are intended for oral administration. The orally disintegrating tablet begins disintegrating in the mouth within seconds, allowing its contents to be subsequently swallowed with or without liquid.
What are the ingredients in APO-olanzapine oral disintegrating tablets?
Each APO-Olanzapine ODT orally disintegrating tablets contains either 5 mg, 10 mg, 15 mg or 20 mg of olanzapine as the active ingredient. It also contains the following inactive ingredients: colloidal anhydrous silica.
Does olanzapine have phenylalanine in it?
The ODT form of olanzapine contains aspartame, which is a source of phenylalanine. Prolonged erection: In rare cases, use of this medication by some men may cause them to develop priapism (a prolonged and painful erection).