What organ system would be affected by Trypanosoma?
Reproductive organs are often affected during trypanosomiasis in both male and female animals [16]. In male animals infected with the T. b. brucei, testis show multiple lesions, including scrotal dermatitis, orchitis and periorchitis.
How does Chagas disease affect the digestive system?
Chagas disease is related to several chronic gastrointestinal disorders resulting from damage to both excitatory and inhibitory enteric motor innervations, leading to megaesophagus, megacolon, megasmall intestine, megagallbladder, megacholedochus, achalasia of the cardia, changes in gastric receptive relaxation, fast …
Does Trypanosoma cause diarrhea?
Acute phase: During this phase, which lasts for the first few weeks or months infection, a person may have no symptoms or mild ones, such as fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, and vomiting.
Does Chagas disease cause constipation?
Another common manifestation of Chagas disease in the gastrointestinal tract is chagasic megacolon. Chronic constipation is the main symptom related to megacolon.
Can Chagas cause constipation?
Chagas disease can also cause gastrointestinal problems, such as severe constipation and difficulty swallowing. Infection is typically spread by contact with the triatomine bug, most commonly found in rural parts of Mexico, Central America, or South America.
How long do Chagas disease symptoms last?
Chagas disease has an acute and a chronic phase. If untreated, infection is lifelong. Acute Chagas disease occurs immediately after infection, and can last up to a few weeks or months. During the acute phase, parasites may be found in the circulating blood.
What are the stages mostly seen in human body in Trypanosoma infection?
Infection occurs in two stages, an initial haemolymphatic stage followed by a meningoencephalitic stage after the trypanosomes invade the central nervous system (CNS). However, many of the signs and symptoms are common to both stages, making it difficult to distinguish between the two stages by clinical features alone.
What are the stages of Trypanosoma?
How does Trypanosoma affect the body?
Fever, severe headaches, irritability, extreme fatigue, swollen lymph nodes, and aching muscles and joints are common symptoms of sleeping sickness. Some people develop a skin rash. Progressive confusion, personality changes, and other neurologic problems occur after infection has invaded the central nervous system.
What is a megacolon?
Megacolon is an abnormal dilation of the colon that is not caused by mechanical obstruction. It is usually accompanied by symptoms such as abdominal discomfort, but may result in serious complications (colonic perforation, peritonitis, and/or sepsis) if left untreated.
How serious is colon infection?
Bacteria spilling from the colon into your abdominal cavity can lead to a life-threatening infection (peritonitis). Death. Rarely, mild to moderate C. difficile infection — but more commonly, serious infection — can quickly progress to fatal disease if not treated promptly.
How does Chagas disease affect the body?
If Chagas disease progresses to the long-lasting (chronic) phase, serious heart or digestive complications may occur. These may include: Heart failure. Heart failure occurs when your heart becomes so weak or stiff that it can’t pump enough blood to meet your body’s needs.
Can you recover from Chagas disease?
To kill the parasite, Chagas disease can be treated with benznidazole or nifurtimox. Both medicines are nearly 100% effective in curing the disease if given soon after infection at the onset of the acute phase, including the cases of congenital transmission.
Can Chagas go away on its own?
Signs and symptoms that develop during the acute phase usually go away on their own. In some cases, if the infection isn’t treated, Chagas disease will advance to the chronic phase.
How does Trypanosoma infect the body?
The disease is mostly transmitted through the bite of an infected tsetse fly but there are other ways in which people are infected: Mother-to-child infection: the trypanosome can cross the placenta and infect the fetus.