What medication should not be taken with grapefruit?
Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin). Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine). Some organ-transplant rejection drugs, such as Neoral and Sandimmune capsule or oral solution (both cyclosporine).
Does anything interact with spironolactone?
Some products that may interact with this drug include: lithium, drugs that may increase the level of potassium in the blood (such as amiloride, cyclosporine, eplerenone, tacrolimus, triamterene, birth control pills containing drospirenone).
Can you eat grapefruit while taking a diuretic?
Do not use grapefruit juice to mix this medication. Some mixtures of medications can lead to serious and even fatal consequences.
What vitamins does spironolactone deplete?
With the use of Aldactazide, potassium excess and potassium depletion are both possible. People taking this combination drug should have their potassium levels monitored by a doctor to determine whether their potassium intake should be increased, reduced, or kept the same.
What vitamins should you not take with spironolactone?
People taking spironolactone should avoid potassium supplements, potassium-containing salt substitutes (Morton Salt Substitute, No Salt, Lite Salt, and others), and even high-potassium foods (primarily fruit).
Why can’t you have grapefruit with blood pressure medicine?
Calcium channel blockers They’re used as part of the treatment of conditions such as high blood pressure (hypertension) and coronary heart disease. Grapefruit juice interacts with some calcium channel blockers and increases the level of the medicine in your blood.
Can you eat bananas while taking spironolactone?
Avoid taking salt substitutes that contain potassium or potassium supplements while taking spironolactone. Try to avoid foods high in potassium (such as avocados, bananas, coconut water, spinach, and sweet potato) because eating these foods may lead to potentially fatal hyperkalemia (high blood potassium levels).
Does grapefruit raise blood pressure?
Citrus fruits, including grapefruit, oranges, and lemons, may have powerful blood-pressure-lowering effects. They’re loaded with vitamins, minerals, and plant compounds that may help keep your heart healthy by reducing heart disease risk factors like high blood pressure ( 4 ).
Is it OK to take vitamin D with spironolactone?
No interactions were found between spironolactone and Vitamin D3.
Can I eat bananas while on spironolactone?
How does grapefruit affect blood pressure?
Studies have shown that eating grapefruit every day can lower systolic blood pressure by as much as five points. This may be due to grapefruit’s high levels of potassium, which neutralize the negative effects of sodium (a common cause of hypertension).
Is it OK to eat grapefruit with blood pressure medicine?
They’re used as part of the treatment of conditions such as high blood pressure (hypertension) and coronary heart disease. Grapefruit juice interacts with some calcium channel blockers and increases the level of the medicine in your blood.
Will eating a grapefruit everyday lower my blood pressure?
Can I take a multivitamin while on spironolactone?
Interactions between your drugs No interactions were found between Celebrate Multivitamin and spironolactone. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Can you eat bananas on spironolactone?
Does spironolactone interact with grapefruit?
Alternatives: Spironolactone (Aldactone), a similar drug to losartan and eplerenone, does not interact with grapefruit. Amlodipine (Norvasc) is a calcium channel blocker like felodipine and nifedipine, which also does not interact with grapefruit ( 6, 8 ).
Why does grapefruit juice block CYP3A4?
Grapefruit juice can block the action of CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body. The amount of the CYP3A4 enzyme in the intestine varies from person to person, says Huang.
How does grapefruit affect drug absorption?
Instead of changing metabolism, grapefruit juice can affect proteins in the body known as drug transporters, which help move a drug into our cells for absorption. As a result, less of the drug enters the blood and the drug may not work as well, Huang says.
What happens if you drink grapefruit juice with nifedipine?
One study found blood levels of nifedipine increased dramatically when taken with about 2 cups (500 mL) of grapefruit juice, compared with no juice. This resulted in a rapid drop in blood pressure, which could be dangerous if unsupervised ( 6 ).