What is quinine hydrochloride?
Quinine hydrochlorideProduct ingredient for Quinine An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
What is quinine hydrochloride good for?
Quinine has been used for the treatment of malaria and associated febrile states, leg cramps caused by vascular spasm, internal hemorrhoids, varicose veins, and pleural cavities after thoracoplasty.
Why was quinine sulfate taken off the market?
In early 2007, FDA banned all prescription quinine products other than Qualaquin. FDA acted in this manner because of a perception that quinine is not effective for this condition and that its risk potential far exceeds its efficacy potential.
What is quinine sulphate 300 mg used for?
Quinine sulfate at a dose of 200–300 mg at night has been used for many years to treat nocturnal leg cramps. Usually idiopathic, these muscle cramps are common, particularly in older patients. Quinine may help by decreasing the excitability of the motor end-plate and increasing the muscle refractory period.
Where does quinine hydrochloride come from?
quinine, drug obtained from cinchona bark that is used chiefly in the treatment of malaria, an infection caused by the protozoan parasite Plasmodium, which is transmitted to humans by the bite of various species of mosquitoes.
What is quinine hydrochloride in tonic water?
Tonic water is a soft drink containing quinine, which gives it a bitter taste. Quinine is a common treatment for malaria. Some people believe that it can also help with leg cramps and restless legs syndrome. Quinine comes from the bark of the cinchona tree.
Is quinine sulfate still available?
A: Federal law expressly prohibits the sale of over-the-counter quinine sulfate products. 21 C.F.R. Sections 310.546 & 310.547. Effective February 13, 2007, the Food & Drug Administration (“FDA”) ordered all manufacturers of prescription quinine sulfate products not approved for marketing by FDA to cease manufacturing.
Is quinine harmful to the body?
Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin, red skin lesions, severe acne or a skin rash, sores or ulcers on the skin, or fever or chills with this medicine. Quinine may cause hypoglycemia (low blood sugar).
How much quinine is too much?
Even three glasses daily should be OK as long as you are not sensitive to quinine. Some susceptible people develop a dangerous blood disorder after even small doses of quinine. Symptoms of quinine toxicity include digestive upset, headache, ringing in the ears, visual disturbances, skin rash and arrhythmias.
Which tonic water is the healthiest?
Best Overall: Fever-Tree Indian Tonic Water It’s made using quinine from the “fever trees” found in the Democratic Republic of Congo. These trees, which are known as cinchona trees, contain quinine in their bark, which is the source of the bitterness in tonic water.
Is quinine sulphate safe to take?
patients should be warned not to exceed the recommended dose. Serious side effects including irreversible blindness and death may occur with overdose. thrombocytopenia is a rare but potentially life-threatening adverse reaction associated with quinine.
Can I buy quinine OTC?
In the United States, quinine tablets are available only by prescription for the treatment of malaria (as Qualaquin). In other countries, quinine may be available for leg cramps by prescription or over-the-counter.
What is the difference between quinine and hydroxychloroquine?
is that quinine is (pharmaceutical drug) a bitter colourless powder, an alkaloid derived from cinchona bark, used to treat malaria and as an ingredient of tonic water while hydroxychloroquine is an antimalarial drug used to reduce inflammation in the treatment of rheumatoid arthritis and lupus.
What are the available forms of quinine sulfate?
Available forms. Quinine is a basic amine and is usually provided as a salt. Various existing preparations include the hydrochloride, dihydrochloride, sulfate, bisulfate and gluconate. In the United States, quinine sulfate is commercially available in 324-mg tablets under the brand name Qualaquin.
What is quinine made of?
Quinine is a basic amine and is usually provided as a salt. Various existing preparations include the hydrochloride, dihydrochloride, sulfate, bisulfate and gluconate.
What is the generic name for quinine?
Quinine is a basic amine and is usually provided as a salt. Various existing preparations include the hydrochloride, dihydrochloride, sulfate, bisulfate and gluconate. In the United States, quinine sulfate is commercially available in 324-mg tablets under the brand name Qualaquin.