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What are the most common side effects of etoposide?

Posted on September 17, 2022 by David Darling

Table of Contents

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  • What are the most common side effects of etoposide?
  • What cancers are treated with etoposide?
  • How much does cisplatin chemo cost?
  • What is the difference between etoposide and etoposide phosphate?

What are the most common side effects of etoposide?

Etoposide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea.
  • vomiting.
  • sores in the mouth and throat.
  • stomach pain.
  • diarrhea.
  • constipation.
  • loss of appetite or weight.
  • unusual tiredness or weakness.

Does etoposide cause cancer?

Injection site reactions may occur while you are receiving this medicine. Tell your doctor right away if you notice swelling, pain, or redness at the injection site. This medicine may cause leukemia (cancer of the blood or bone marrow) in rare cases.

What cancers are treated with etoposide?

What Etoposide Is Used For: Testicular, bladder, prostate, lung, stomach, and uterine, cancers. Hodgkin’s and non-Hodgkin’s lymphoma, mycosis fungoides, Kaposi’s sarcoma, Wilm’s tumor, rhabdomyosarcoma, Ewing’s sarcoma, neuroblastoma, brain tumors.

Can etoposide cause heart problems?

In 100 people receiving Bleomycin, Etoposide, Cisplatin, from 4 to 20 may have: Blood clot which may cause swelling, pain, shortness of breath. Heart failure or heart attack which may cause chest pain, shortness of breath, swelling of ankles, and tiredness.

How much does cisplatin chemo cost?

The cost for cisplatin intravenous solution (1 mg/mL) is around $16 for a supply of 50 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans….Intravenous Solution.

Quantity Per unit Price
100 milliliters $0.22 $22.10
200 milliliters $0.17 $34.70

What is etoposide FDA approved for?

On March 27, 2020, the Food and Drug Administration approved durvalumab (IMFINZI, AstraZeneca) in combination with etoposide and either carboplatin or cisplatin as first-line treatment of patients with extensive-stage small cell lung cancer (ES-SCLC).

What is the difference between etoposide and etoposide phosphate?

Etoposide phosphate is a water soluble ester of etoposide (commonly known as VP-16), a semi-synthetic derivative of podophyllotoxin. The water solubility of etoposide phosphate lessens the potential for precipitation following dilution and during intravenous administration.

How long does etoposide stay in your system?

Pharmacokinetics. On intravenous administration, the disposition of Etoposide is best described as a biphasic process with a distribution half-life of about 1.5 hours and terminal elimination half-life ranging from 4 to 11 hours.

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