What is a coumarin medical?
Warfarin – a coumarin – with brand name, Coumadin, is a prescription drug used as an anticoagulant to inhibit formation of blood clots, and so is a therapy for deep vein thrombosis and pulmonary embolism.
Where can coumarin be found?
It is found in different plant sources such as vegetables, spices, fruits, and medicinal plants including all parts of the plants-fruits, roots, stems and leaves. Coumarin is found in high concentrations in certain types of cinnamon, which is one of the most frequent sources for human exposure to this substance.
What are coumarin derivatives?
Coumarin derivatives (4-hydroxycoumarin compounds) are oral anticoagulants (OA) that prevent vitamin K from acting as a cofactor in the hepatic synthesis of the vitamin K-dependent coagulation factors II, VII, IX, and X (as well as the anticoagulants, proteins C and S).
Is coumarin bad for humans?
Despite its sweet flavor and pleasant aroma, coumarin is a chemical that can have serious effects on health when consumed in high amounts. In fact, high doses have been linked to liver damage, impaired cognitive development and even cancer formation in both animal and human studies.
Why coumarin is not healthy?
Animal studies have shown that eating too much coumarin, which is abundant in Cassia cinnamon, may increase the risk of certain cancers ( 3 ). For example, studies in rodents have found that eating too much coumarin can cause cancerous tumors to develop in the lungs, liver, and kidneys (8, 9, 10 ).
What foods contain coumarin?
Coumarin is a naturally occurring sweet-smelling compound found in many plants, including cinnamon, tonka beans, and sweet clover. High amounts of coumarin can be found in cassia cinnamon (also known as true cinnamon), whereas the Ceylon variety typically contains only traces.
Why is coumarin banned in US?
The tonka bean’s distinct flavor is thanks to coumarin, a chemical compound that has been banned in the United States since 1954 because it can cause liver problems in high concentrations.
Is coumarin in all cinnamon?
Despite this broad acceptance, cassia cinnamon — the type eaten most often in North America — contains a substance called coumarin that can be dangerous when consumed in large quantities.
What is the healthiest cinnamon to eat?
Ceylon cinnamon contains all of the health-promoting properties of cinnamon with none of the toxic properties, which is why it’s the healthiest type of cinnamon.
Does Walmart carry Ceylon cinnamon?
Spring Valley Ceylon Cinnamon Dietary Supplement, 1,200 mg, 120 count – Walmart.com.
Which brand of cinnamon is Ceylon?
Best Organic: Frontier Co-op Ground Ceylon Cinnamon It’s sourced from Sri Lanka and has a sweet and warm flavor that lends itself well to cookies, cakes, and other baked goods.
Is McCormick ground cinnamon real cinnamon?
The cinnamon bark is harvested directly from the tree—McCormick sources premium quality whole cinnamon, which mitigates the chance for added ingredients and contamination that could be encountered by sourcing a pre-ground product.