How is CSW and SIADH diagnosed?
Hypovolemia, as seen in CSW, is diagnosed most reliably when CVP monitoring is available [13] . CSW is marked by a low CVP (<6), whereas SIADH has a normal or increased CVP (6 – 10) [20] [27] .
How is salt loss of nephropathy diagnosed?
A diagnosis of salt-losing nephropathy was made and sodium correction was done with 3% saline and fludrocortisone. She responded well to therapy. The cause of hyponatremia was considered renal tubular dysfunction together with elevated antidiuretic hormone level.
What is the sodium level in SIADH?
In SIADH, the urine sodium concentration is usually above 40 mEq/L, the serum potassium concentration is normal, there is no acid-base disturbance, and the serum uric acid concentration is frequently low [1]. (See “Diagnostic evaluation of adults with hyponatremia”.)
What is Hypokalemic nephropathy?
Hypokalemic nephropathy is a tubulointerstitial disease that clinically presents as prolonged hypokalemia, polyuria, metabolic alkalosis, proteinuria, and progressive loss of renal function.
What are the causes of Pseudohyponatremia?
The most common cause of pseudohyponatremia is due to severely elevated levels of cholesterol. [2] In serum blood samples taken from patients with severe hypertriglyceridemia, the sample may appear overtly lipemic, hyper viscous, or discolored from the overwhelming presence of insoluble triglycerides.
What is CSW%?
CSW rate or called plus swinging strike percentage has taken the baseball world by storm. Created by Nick Pollack and Alex Fast of Pitcher List, CSW rate is called strikes plus whiffs, divided by total pitches. Nick and Alex first used the stat on their podcast, leading to a research article that won awards.
Is cerebral salt wasting a cause of hyponatremia?
Topic Outline. Cerebral salt wasting (CSW) is another potential cause of hyponatremia in those with CNS disease, particularly patients with subarachnoid hemorrhage. CSW is characterized by hyponatremia and extracellular fluid depletion due to inappropriate sodium wasting in the urine [ 5 ]. However, some authorities contend…
What is cerebral salt wasting (CSW)?
Cerebral salt wasting (CSW) is defined as excessive urinary sodium and subsequent hyponatremia and dehydration in individuals with intracranial disease. From:Pediatric Secrets (Fifth Edition), 2011
What is salt wasting of the brain?
Cerebral Salt Wasting 1 also now known as renal salt wasting 2 hyponatraemia not always required to make diagnosis, but often present 3 cerebral lesion + excess renal loss of Na+ and Cl- 4 cerebral lesions: SAH, TBI, tumour
What is the pathophysiology of salt wasting?
Cerebral salt wasting (CSW) is defined as excessive urinary sodium and subsequent hyponatremia and dehydration in individuals with intracranial disease. The mechanism is not clear. CSW typically develops in the first week after brain injury and generally resolves over time. Both CSW and SIADH are associated with hyponatremia.