How much weight do you lose on zonisamide?
The zonisamide group (n = 19) had a mean weight loss of 9.2 kg (1.7 kg) (9.4% loss) at week 32 compared with 1.5 kg (0.7 kg) (1.8% loss) for the placebo group (n = 17) (t = 4.0; P<. 001). Zonisamide was tolerated well, with few adverse effects.
Does zonegran cause weight loss?
Zonegran is already FDA approved. It’s used to treat epilepsy. During clinical trials, epilepsy patients treated with the drug lost weight. That was bad for them — but it might be a good weight-loss drug.
Do you gain weight on zonisamide?
Longitudinal assessment indicated that zonisamide was associated with a significantly slower rate of BMI and weight increases compared with placebo (P = . 01). No patients in the zonisamide group experienced significant weight gain, compared with 33% of placebo-treated patients (P = . 009).
Will zonisamide help me lose weight?
The antiepileptic drug zonisamide moderately enhances the weight loss achieved with diet and lifestyle counseling, but is associated with a high incidence of adverse events.
Which is better for weight loss topiramate or zonisamide?
Weight reduction was not statistically different between topiramate or zonisamide. Anticonvulsants were associated with an increase in body mass index, yet the benefits of the two anticonvulsants on weight loss remained despite the counteractive effects of antipsychotics.
Does zonisamide give you energy?
Zonisamide (Zonegran) can cause you to become sleepy. Be careful driving or doing anything that could be dangerous until you know how this medication affects you. Try to avoid anything else that could cause you to become sleepy such as narcotic pain medications, allergy medications, and alcohol.
Can zonisamide cause anger?
This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away.
Does zonisamide cause memory loss?
Zonisamide administered in a high, acute dose impairs the spatial memory. The drug given repeatedly disturbs spatial memory in the initial phase of the study. Zonisamide administered repeatedly impairs emotional memory.
Does zonisamide cause hair loss?
Hair loss is a side effect for about 5% of people that take zonegran. It happened to me, it took me quite a few months to notice, by which time I had lost about half of my hair (lucky for me its thick).
Does zonisamide suppress appetite?
One of the noted side effects of zonisamide is appetite suppression.
Does zonisamide cause forgetfulness?
Why has zonisamide been discontinued?
Zonisamide discontinuation due to psychiatric and cognitive adverse events – PMC. The . gov means it’s official. Federal government websites often end in .
Has zonisamide been recalled 2022?
On April 25, 2022, Glenmark announced a consumer-level recall of several lots of zonisamide capsules due to gaps in the microbiology quality control system or due to lack of stability data. Zonisamide is indicated as adjunctive therapy in the treatment of partial seizures in adults with epilepsy.
Does zonisamide affect memory?
Why is zonisamide being discontinued?
Has zonisamide been discontinued?
ZONEGRAN (zonisamide) is indicated as adjunctive therapy in the treatment of partial seizures in adults with epilepsy. ZONEGRAN (zonisamide) capsules, 50 mg, is currently listed in the “Discontinued Drug Product List” section of the Orange Book.
What is Zonegran (zonisamide)?
What is Zonegran? Zonegran ( zonisamide) is a sulfa drug with anti-convulsant effects. Zonegran is a prescription medicine used together with other medicines to treat partial partial seizures in adults with epilepsy. It is not known if Zonegran is safe or effective in children under 16 years of age.
How much Zonegran should I take for seizures?
Zonegran Dosage and Administration. Zonegran (zonisamide) is recommended as adjunctive therapy for the treatment of partial seizures in adults. Safety and efficacy in pediatric patients below the age of 16 have not been established. Zonegran should be administered once or twice daily, using 25 mg or 100 mg capsules.
How long does it take for Zonegran to start working?
This medication should start having effects within a few hours, but you may not experience the full effects of seizure prevention until you have been regularly taking it as prescribed for several days. 3 What are the side effects of Zonegran?
Is Zonegran safe for children?
It is not known if Zonegran is safe or effective in children under 16 years of age. You should not use Zonegran if you are allergic to zonisamide, or to other sulfa drugs such as sulfamethoxazole (Gantanol), sulfisoxazole (Gantrisin), or sulfamethoxazole-trimethoprim (Bactrim, Septra, Sulfatrim, SMX-TMP, and others).