Is Marburg virus the same as Ebola?
Ebola virus is part of the Filoviridae family, which also includes Marburg virus. Marburg virus disease was first recognized in 1967 and is characterized by the same symptoms and transmission routes as Ebola virus disease.
What are variants of MS?
Four disease courses have been identified in multiple sclerosis: clinically isolated syndrome (CIS), relapsing-remitting MS (RRMS), primary progressive MS (PPMS), and secondary progressive MS (SPMS).
Is Marburg virus curable?
No cure or effective treatment exists for Marburg virus disease, making preventing the disease critical through steps like personal protective equipment and safe handling of body fluids.
Is there a cure for Marburg?
There is no specific treatment for Marburg virus disease. Supportive hospital therapy should be utilized, which includes balancing the patient’s fluids and electrolytes, maintaining oxygen status and blood pressure, replacing lost blood and clotting factors, and treatment for any complicating infections.
How common is Marburg?
Marburg virus disease (MVD) is a rare but severe hemorrhagic fever which affects both people and non-human primates.
What is the death rate of Marburg?
The case-fatality rate for MVD is between 23-90%. For a complete listing of the case fatality rates for each outbreak, please see the History of Outbreaks table.
Is Marburg virus helical?
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP–RNA complex.
What symptoms are suggestive of MS?
Those symptoms include loss of vision in an eye, loss of power in an arm or leg or a rising sense of numbness in the legs. Other common symptoms associated with MS include spasms, fatigue, depression, incontinence issues, sexual dysfunction, and walking difficulties.
What is Marburg acute multiple sclerosis?
Marburg acute multiple sclerosis, also known as Marburg multiple sclerosis or acute fulminant multiple sclerosis, is considered one of the multiple sclerosis borderline diseases, which is a collection of diseases classified by some as MS variants and by others as different diseases.
What is the Marburg virus?
The Marburg virus is transmitted to people from fruit bats and spreads among humans through human-to-human transmission. The Marburg virus causes severe viral haemorrhagic fever in humans. The average MVD case fatality rate is around 50%.
What are the signs and symptoms of Marburg variant?
Marburg variant is typically seen in younger patients 1,4. Symptoms may be preceded by fevers and are typically monophasic. Areas of demyelination demonstrate marked macrophage infiltration, marked associated inflammation, and extensive tissue destruction, necrosis and axonal damage and necrosis 2,4 .
What is the relationship between Ebola virus and Marburg virus?
Marburg virus is the causative agent of Marburg virus disease (MVD), a disease with a case fatality ratio of up to 88%. Marburg virus disease was initially detected in 1967 after simultaneous outbreaks in Marburg and Frankfurt in Germany; and in Belgrade, Serbia. Marburg and Ebola viruses are both members of the Filoviridae family (filovirus).