What are the properties of polymeric nanoparticles?
Among different delivery systems, polymeric carriers have several properties such as: easy to synthesize, inexpensive, biocompatible, biodegradable, non-immunogenic, non-toxic, and water soluble.
What are polymer based nanomaterials?
Polymeric nanomaterials are drug transporters made of natural, synthetic, or semisynthetic polymers in the nanoscale range. Silicon nanospheres, carbon nanotubes (CNTs), and chitosan are important examples of polymeric nanomaterials.
What is the main advantage of polymer in polymeric nanoparticle?
Most important advantages offered by the polymeric nanoparticles include the following: (1) provide controlled release to the desired site, (2) provide stability to labile molecules (e.g., proteins), and (3) provide ability to modify surfaces with ligands for stealth and targeted drug delivery purposes [30].
Why polymers are used in nanoparticles?
The polymer provides protection to the active molecules to the delivery site; especially through the gastrointestinal tract. Generally, natural polymers are nontoxic, biocompatible, and biodegradable. Polysaccharides and proteins are the commonly used wall materials for the fabrication of polymeric nanoparticles.
How do you make polymeric nanoparticles?
However, there are various methods used for the preparation of polymeric nanoparticles such as desolvation, dialysis, ionic gelation, nanoprecipitation, solvent evaporation, salting out, spray drying and supercritical fluid. However, the choice of an appropriate method depends upon various factors.
What is a polymeric material?
Polymers are materials made of long, repeating chains of molecules. The materials have unique properties, depending on the type of molecules being bonded and how they are bonded. Some polymers bend and stretch, like rubber and polyester. Others are hard and tough, like epoxies and glass.
What is polymer example?
Examples of Polymers Natural polymers (also called biopolymers) include silk, rubber, cellulose, wool, amber, keratin, collagen, starch, DNA, and shellac.
What is a polymeric part?
A polymer (/ˈpɒlɪmər/; Greek poly-, “many” + -mer, “part”) is a substance or material consisting of very large molecules, or macromolecules, composed of many repeating subunits. Due to their broad spectrum of properties, both synthetic and natural polymers play essential and ubiquitous roles in everyday life.
What are polymeric nanoparticles?
Polymeric nanoparticles are synthetic polymers with a size ranging from 10 to 100 nm. Common synthetic polymeric nanoparticles include polyacrylamide, polyacrylate, and chitosan. Drug molecules can be incorporated either during or after polymerization.
What is polymer nanocomposite?
Polymer nanocomposite. Polymer nanoscience is the study and application of nanoscience to polymer-nanoparticle matrices, where nanoparticles are those with at least one dimension of less than 100 nm . The transition from micro- to nano-particles lead to change in its physical as well as chemical properties.
What are semiconductor nanoparticles made of?
Metal, dielectric, and semiconductor nanoparticles have been formed, as well as hybrid structures (e.g., core–shell nanoparticles). Nanoparticles made of semiconducting material may also be labeled quantum dots if they are small enough (typically sub 10 nm) that quantization of electronic energy levels occurs.
What is liposome nanoparticle?
A prototype nanoparticle of semi-solid nature is the liposome. Various types of liposome nanoparticles are currently used clinically as delivery systems for anticancer drugs and vaccines.