What company manufactures Gleevec?
Teva Pharmaceutical Industries has announced the launch of a generic version of imatinib mesylate, which is currently manufactured by Novartis and is sold under the brand name Gleevec.
What is Glivec used for?
This medication is used to treat certain types of cancer (such as acute lymphoblastic leukemia, chronic myeloid leukemia, gastrointestinal stromal tumors, and myelodysplastic/myeloproliferative diseases). It works by slowing or stopping the growth of cancer cells.
What is the brand name of imatinib?
Gleevec is the trade name for the generic drug name Imatinib Mesylate. STI-571 is another name for Imatinib Mesylate. In some cases, health care professionals may use the trade name Gleevec or other name STI-571 when referring to the generic drug name Imatinib Mesylate.
Who invented imatinib?
Imatinib was invented in the late 1990s by biochemist Nicholas Lyndon then working for Ciba-Geigy (now Novartis), and its use to treat CML was driven by Brian Druker, an oncologist at the Dana-Farber Institute. The first clinical trial of Imatinib took place in 1998 and the drug received FDA approval in May 2001.
When did Gleevec go generic?
In February 2016, a generic version of imatinib (Gleevec), the groundbreaking tyrosine kinase inhibitor, was made available in the United States.
How long has Gleevec been on the market?
Even though Gleevec has been on the market for more than 15 years, it still costs more than $140,000 a year, according to Dr.
Is imatinib generic?
Yes, there is a generic version of Gleevec known as imatinib mesylate. Imatinib comes in a 100-mg and 400-mg oral tablet. Generic imatinib was approved in the U.S. in Dec. 2015 and was first manufactured by Sun Pharmaceuticals.
Does Gleevec make you lose your hair?
Hair loss. Gleevec can cause hair loss in people taking it, although this isn’t a common side effect of the drug. Keep in mind that hair loss during cancer treatment is usually temporary. In general, hair lost while taking Gleevec is expected to grow back after you stop taking the drug.
What is the mechanism of action of imatinib?
Mechanism of Action Imatinib mesylate is a protein-tyrosine kinase inhibitor that inhibits the bcr-abl tyrosine kinase, the constitutive abnormal tyrosine kinase created by the Philadelphia chromosome abnormality in chronic myeloid leukemia (CML).
Is Gleevec and imatinib the same?
The drug, named STI-571 and later renamed imatinib (Gleevec), blocks the activity of the BCR-ABL fusion protein.
Can I take vitamins with Gleevec?
It may not be safe to use certain prescription or over-the-counter (OTC) medications, vitamins, herbal products or some foods with Gleevec. These products may affect blood levels of Gleevec or your other medicines. This may increase side effects or make your medications less effective.
Can I drink coffee while taking Gleevec?
during Gleevec use may want to avoid certain foods and beverages (i.e., spicy foods, chocolate, caffeine, citrus juice, dairy products, etc.) that may exacerbate these unwanted effects.
What is Glivec used to treat?
GLIVEC ® (imatinib) is indicated for: The treatment of adult patients with KIT (CD117)-positive unresectable and/or metastatic malignant gastrointestinal stromal tumours (GIST) The adjuvant treatment of adult patients who are at significant risk of relapse following resection of KIT (CD117)-positive GIST.
Is Glivec® (imatinib) available outside the US?
This is an international site for Glivec® (imatinib) and is intended for Health Care Professionals outside the US. GLIVEC®(imatinib) is approved for use in more than 116 countries around the world. Healthcare Professionals
What is the optimal daily dose of Glivec for gist?
In 2 clinical studies, the daily dose of GLIVEC was escalated to 800 mg in patients progressing at lower daily doses and achieved an overall clinical benefit of 26%1 In clinical trials in KIT+ GIST patients, treatment with GLIVEC was continued until disease progression1 Administration
Why choose Novartis Oncology’s Glivec?
Behind every GLIVEC tablet is our promise of authenticity to you and your patients. As part of this promise, Novartis Oncology is proud to deliver each prescription in packaging that is more informative and secure than ever before. The pharmacologic makeup and dose availability of GLIVEC remain unchanged.