What is a lipoprotein particle profile?
Lipoprotein Particle Profile (LPP®) Studies have found that it is actually the lipoprotein particles that carry the cholesterol throughout the blood, not the cholesterol within them, that are responsible for key steps in plaque formation and the development of cardiovascular disease.
What is an LPP test?
The LPP™ test is the most advanced test available to predict heart disease risk, much more so than standard cholesterol testing. It measures the lipoprotein particles directly giving a more precise evaluation of their size. High numbers of small, dense LDL particles can ultimately cause cardiovascular disease.
What is LDL particle size test?
The LDL particle number measures the actual number of LDL particles that carry LDL cholesterol per liter of plasma. In addition to the number of LDL particles, advanced lipid tests report the size of these LDL particles, which may help your provider diagnose the cause of your cholesterol abnormality.
What is lipid Profile test used for?
A complete cholesterol test — also called a lipid panel or lipid profile — is a blood test that can measure the amount of cholesterol and triglycerides in your blood.
How do I lower my LDL particle number?
Can I reduce my amount of small, dense LDLs?
- Eat a diet very rich in soluble fiber (BYOBB) – Beans, Yams, Oats, Barley, and Berries.
- Eat fewer refined carbohydrates.
- Eat much less saturated and trans fats and cholesterol.
- Exercise regularly, and.
- Lose excess weight.
What is a normal LPA level?
Most people have Lp(a) levels in the range of under 5 to 29 milligrams per deciliter (mg/dL), which roughly equals under 13 to 73 nanomoles per liter (nmol/L.
Are small or large LDL particles good?
Smaller, more tightly packed LDL has an easier time getting into arteries. Larger, fluffier particles may be less dangerous. Also, research suggests that a key protein on LDL called apolipoprotein B (apoB) is an important contributor for heart disease risk.
How do you treat high LDL particle number?
For example, if you have a large number of LDL-P and they’re small, the two best things to treat those are niacin and omega-3 fatty acids, and also getting a patient on a low-carbohydrate diet, particularly one that is low in sugar and refined carbohydrates.
Is High HDL p good?
High-density lipoprotein (HDL) cholesterol concentration (HDL-C) is an established atheroprotective marker, in particular for coronary artery disease; however, HDL particle concentration (HDL-P) may better predict risk.
What does HDL P mean?
High-density Lipoprotein Particle
High-density Lipoprotein Particle Number, Total.
Can you change LDL particle size?
You can do some things to reduce the formation of small, dense LDL in the blood. Although you cannot do much if you have inherited raised small, dense LDL, you can make some changes to your lifestyle to lower your chances of developing this particle.
What is a high level of LPA?
In the US guidelines, elevated Lp(a)—defined as ≥ 50 mg/dL or ≥ 125 nmol/L—is considered a “risk-enhancing” factor that can be used to determine how aggressively to treat LDL cholesterol levels.
How do you treat a high LPA?
Other treatments shown to help lower Lp(a) levels include:
- PCSK9 inhibitors. These reduce levels by 20-30%, but they are not currently licenced for lowering Lp(a).
- Lipoprotein apheresis. This is a weekly-fortnightly treatment similar to renal dialysis which can reduce Lp(a) levels by up to 75%.
What is lipoprotein particle profile (LPP)?
Now there is an advanced cholesterol testing technology which accurately measures both the density and number of lipoprotein particles. This test is the Lipoprotein Particle Profile™, or LPP™, from SpectraCell Laboratories.
What is the LPP™ test?
SpectraCell’s LPP™ test is a proprietary technology originally developed at Texas A&M University that separates the lipoproteins in blood serum by density using analytical ultracentrifugation, the CDC gold standard for lipoprotein testing, then measures the particles photometrically.
What is LPP cholesterol and why is it important?
Lipoprotein Particle Profile (LPP®) Cholesterol has historically been used as the standard indicator for cardiovascular disease, often being classified as “good” (HDL) or “bad” (LDL).
What is the difference between NMR® and LPP®?
While both NMR and LPP® report lipoprotein particles, NMR-derived particle numbers only identify patients at high risk of heart disease, while Spectracell’s LPP®identifies high-risk patients andreports data on how to best treat the patient. This is key because the most effective course of treatment depends on which specific lipoprotein is elevated.