What is a Myofibroma mean?
Myofibroma is a solitary nodular tumor of the soft tissue, bone, or internal organs that affects all ages. The tumor may present as single or multiple nodules.
How common is Myofibroma?
IM is found at birth in about 1 out of 150,000 babies. Some cases of IM may not be diagnosed or correctly diagnosed. For this reason, IM may be more common than we think. It is most common in babies and young children.
What is myofibroblastic proliferation?
Pseudosarcomatous myofibroblastic proliferation (PMP) is a rare disease entity of unknown etiology and pathogenesis. PMP is also known as an inflammatory pseudotumor (IPT) or inflammatory myofibroblastic tumor (IMT), and it is characterized by myofibroblast proliferation and inflammatory cell infiltration.
What is the most common benign tumor in infancy?
Head and neck hemangiomas are the most common benign soft tissue tumors in neonates.
What is myofibroblastic tumor?
An Inflammatory myofibroblastic tumor (IMT) is an uncommon, usually benign (non-cancerous) tumor made up of cells called myofibroblastic spindle cells. It usually develops in children or young adults, but can affect people of any age.
Where does rhabdomyosarcoma occur?
Overview. Rhabdomyosarcoma (RMS) is a rare type of cancer that forms in soft tissue — specifically skeletal muscle tissue or sometimes hollow organs such as the bladder or uterus. RMS can occur at any age, but it most often affects children.
How do you treat inflammatory myofibroblastic tumors?
The only known effective therapy for IMT is complete surgical resection (9,13,28). In most cases, further aggressive measures, including chemotherapy and radiation therapy, are avoided due to the generally benign clinical course and limited biologic potential of these tumors.
What does myofibroblastic tumor mean?
A rare type of cancer that is made up of smooth muscle cells, connective tissue cells, and certain types of immune cells. It can occur anywhere in the body, but it usually occurs in the lung, abdomen, pelvis, or back of the abdomen.
Why are tumors harmful?
Malignant tumors are cancerous. They develop when cells grow uncontrollably. If the cells continue to grow and spread, the disease can become life threatening. Malignant tumors can grow quickly and spread to other parts of the body in a process called metastasis.
How common is inflammatory myofibroblastic tumor?
How common is inflammatory myofibroblastic tumor? IMT is very rare and occurs in less than one in one million people. An estimated 150-200 people are diagnosed in the US annually.
What causes inflammatory myofibroblastic tumor?
IMTs may recur, and become locally invasive and/or spread (metastasize) to other parts of the body. However, malignant (cancerous) IMTs are rare. The underlying cause of IMTs is poorly understood. Some cases have been linked to translocations involving the ALK gene.