What is Actraphane used for?
Actraphane is used to treat diabetes. The medicine can only be obtained with a prescription.
Is actraphane a fast-acting insulin?
Actraphane is a dual-acting human insulin. It is a biphasic formulation containing both fast-acting and long-acting insulin. Actraphane is administered subcutaneously by injection in the thigh, the abdominal wall, the gluteal region or the deltoid region.
What is the mechanism of action of NPH insulin?
Mechanism of Action It acts as basal insulin and stimulates the liver to promote hepatic glycogen synthesis, fatty acid metabolism for lipoprotein synthesis. In skeletal muscles, it promotes glycogen and protein synthesis.
What is the mechanism of action of actrapid?
ATC code: A10AB01. Mechanism of action and pharmacodynamic effects The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.
When do you inject actraphane?
The injection site should be changed for each injection. The patient’s blood glucose (sugar) should be tested regularly to find the lowest effective dose. The usual dose is between 0.3 and 1.0 international units (IU) per kilogram body weight per day. Actraphane is given 30 minutes before a meal.
What are the side effects of actraphane?
Side effects of Actraphane Hm Injection 10ml
- Low blood sugar (Hypoglycaemia)
- Lightheadedness.
- Dizziness.
- Anxiety.
- Nervousness.
- Tiredness.
- Feeling hungry.
- Visual disturbances.
What is the generic name for actraphane?
Pioglitazone (oral antidiabetic medicine used for the treatment of type 2 diabetes mellitus) Some patients with long-standing type 2 diabetes mellitus and heart disease or previous stroke who were treated with pioglitazone and insulin experienced the development of heart failure.
What happens if non diabetic takes insulin?
In non-diabetics,it can lead to hypoglycemic coma which can have varied outcome from complete reversal to death.
Is NPH insulin fast or slow acting?
NPH insulin is considered intermediate-acting insulin because it lasts for about half a day. It takes longer to act than the natural insulin in your body. NPH is often mixed with regular or rapid-acting insulin to combine the benefits.
Is insulatard and mixtard same?
Mixtard is a mixture of fast-acting insulin and long-acting insulin. This means that it will start to lower your blood sugar about half an hour after you take it, and the effect will last for approximately 24 hours. Insulatard contains a type of insulin called isophane insulin.
What happens if you inject a normal person with insulin?
Unfortunately, the first place that is affected in case of an overdose is the brain; it can lead to a comatose condition or death. Depending on the dosage, you can die within an hour or two,” he says. If a non-diabetic patient is injected with insulin, the degree of the fall of the sugar level is rapid.
How is actraphane made?
The active substance in Actraphane, human insulin, is produced by a method known as ‘recombinant technology’: the insulin is made by yeast cells into which a gene (DNA) has been introduced, which makes them able to produce insulin.
What is the pharmacokinetics of actraphane?
Actraphane is a dual-acting insulin. action is up to 24 hours. Insulin in the blood stream has a half-life of a few minutes. Consequently, the time-action profile of an insulin preparation is determined solely by its absorption characteristics. subcutaneous fat, type of diabetes). The pharmacokinetics of insulin products are therefore affected by
What is the difference between actraphane 40 and actraphane 50?
Actraphane contains both fast-acting (soluble) and long-acting (isophane) insulin: Actraphane 30: soluble insulin 30% and isophane insulin 70%; Actraphane 40: soluble insulin 40% and isophane insulin 60%; Actraphane 50: soluble insulin 50% and isophane insulin 50%.
What is actraphane 50% insulin?
Actraphane is a suspension for injection that contains the active substance human insulin. It is available as vials, cartridges (Penfill) or prefilled pens (InnoLet or FlexPen). Actraphane contains both fast-acting (soluble) and long-acting (isophane) insulin: Actraphane 50: soluble insulin 50% and isophane insulin 50%.