What is nephrotic syndrome PPT?

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Definition Nephrotic syndrome is a clinical complex characterized by a number of renal and extrarenal features, most prominent of which are  Proteinuria (in practice > 3.0 to 3.5gm/24hrs),  Hypoalbuminemia,  Edema,  Hypertension  Hyperlipidemia,  Lipiduria and  Hypercoagulabilty. 3.

What is childhood nephrotic syndrome?

Nephrotic syndrome is a condition that causes the kidneys to leak large amounts of protein into the urine. This can lead to a range of problems, including swelling of body tissues and a greater chance of catching infections.

What is the clinical presentation of a child with nephrotic syndrome?

The first sign of nephrotic syndrome in children is usually swelling of the face; this is followed by swelling of the entire body. Adults can present with dependent edema. Foamy urine may be a presenting feature. Fatigue and loss of appetite are common symptoms.

What is the first line of therapy for managing a child with nephrotic syndrome?

Standard first-line therapy for initial presentation of idiopathic nephrotic syndrome is 6 weeks of daily corticosteroids, followed by 6 weeks of alternate-day therapy (2).

How many types of nephrotic syndrome are there?

There are thought to be two forms of nephrotic syndrome, minimal change disease (MCD) and focal sclerosis (FSGS).

Is nephrotic syndrome curable in child?

Even though the nephrotic syndrome does not have a specific cure, the majority of children “outgrow” this disease in their late teens or in early adulthood. Some children will have only one attack of the syndrome.

Is there cure for children nephrotic syndrome?

Urine tests. A urinalysis can reveal abnormalities in your urine,such as large amounts of protein.

Blood tests. A blood test can show low levels of the protein albumin and often decreased levels of blood protein overall.

Kidney biopsy. Your doctor might recommend removing a small sample of kidney tissue for testing.

How dangerous is nephrotic syndrome?

Your urine may appear frothy.

Tiredness,lethargy and a poor appetite.

Diarrhoea and/or being sick (vomiting) – especially in children.

If the nephrotic syndrome persists for a long time then you may develop wasting of your muscles and your nails may become white (called leukonychia).

What are some signs of nephrotic syndrome?

Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. Other symptoms may include weight gain, feeling tired, and foamy urine. Complications may include blood clots, infections, and high blood pressure.

What is the best treatment for nephrotic syndrome?

Proteinuria: podocytes damage allows the protein to pass into the tubules of the nephron.

Hypoalbuminemia: the mass loss of protien via urine such as albumin from the circulation results in Hypoalbuminemia in the blood.

Hypercholesterolemia: Due to Hypoalbuminemia,liver production is stimulated.