Which drug is used in Rntcp Programme?
The RNTCP will be using a standardized treatment regimen (STR), comprising of 6 drugs (kanamycin, ofloxacin, ethionamide, pyrazinamide, ethambutol, and cycloserine) during 6–9 months of the Intensive Phase and 4 drugs (ofloxacin, ethionamide, ethambutol, and cycloserine) during the 18 months of the Continuation Phase.
WHO latent TB guidelines?
Treatment options recommended for LTBI include: 6-month daily isoniazid, or 9 month daily isoniazid, or 3 month weekly rifapentine plus isoniazid, or 3–4 month daily isoniazid plus rifampicin, or 3–4 month daily rifampicin alone. (Strong recommendation, moderate to high quality of evidence.)
What is the treatment protocol for tuberculosis?
The preferred regimen for treating adults with TB remains a regimen consisting of an intensive phase of 2 months of isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol (EMB) followed by a continuation phase of 4 months of INH and RIF.
WHO recommended TB treatment?
For treatment of new cases of pulmonary or extrapulmonary TB, WHO recommends a standardized regimen consisting of two phases. The initial (intensive) phase uses four drugs (rifampicin, isoniazid, pyrazinamide and ethambutol) administered for two months.
What is the second line drug for TB?
Kanamycin, Capreomycin and Amikacin are injectable second-line. Bedaquiline and Delamanid are new drugs. Ethambutol, Pyrazinamide, Thioamides, Cycloserine, Para-aminosalicylic acid, Streptomycin, and Clofazimine are possibly effective.
How is latent and active TB different?
Persons with latent TB infection are not infectious and cannot spread TB infection to others.
- Usually has a skin test or blood test result indicating TB infection.
- Has a normal chest x-ray and a negative sputum test.
- Has TB bacteria in his/her body that are alive, but inactive.
- Does not feel sick,
What is first line treatment for TB?
Of the approved drugs, isoniazid (INH), rifampin (RIF), ethambutol (EMB), and pyrazinamide (PZA) are considered first-line anti-TB drugs and form the core of standard treatment regimens (Figure 6.4) (Table 6.2). Rifabutin (RBT) and rifapentine (RPT) may also be considered first- line drugs under certain circumstances.
What are the third line drugs for TB?
| Grouping of drugs | Drugs line category |
|---|---|
| Group 1 | Isoniazid, rifampicin, ethambutol, pyrazinamide |
| Second-line anti-tuberculosis drugs | |
| Group 2 | Moxifloxacin, high dose levofloxacin (fluoroquinolones) |
| Group 3 | Linezolid, delamanid, bedaquiline (newer drugs with increased evidence) |
What is 1st line and 2nd line drugs?
First-line antituberculosis drugs- Isoniazid (INH), rifampicin (RIF), ethambutol (EMB), pyrazinamide (PZA) and streptomycin (SM). Second-line antituberculosis drugs- Sub divided into two. Fluoroquinolones- Ofloxacin (OFX), levofloxacin (LEV), moxifloxacin (MOX) and ciprofloxacin (CIP).
What is the full form of dots?
The full form of DOTS is the Directly Observed Therapy, Short-course. It is also known as TB – DOTS. It refers to a strategy aimed at curing and reducing the risk of TB (tuberculosis) cases.