Why is cilazapril no longer available in NZ?
The supplier of cilazapril with hydrochlorothiazide (Apotex) informed PHARMAC it will no longer be able to supply this medicine in New Zealand. The current supply is likely to run out by the end of 2020.
Is cilazapril available in New Zealand?
News Update: cilazapril with hydrochlorothiazide will no longer be available in New Zealand. Patients currently prescribed cilazapril + hydrochlorothiazide combination tablets will need to transition to a different combination medicine or antihypertensive regimen.
What are the side effects of taking cilazapril?
Side effects
- a dry irritating cough (this often improves with time)
- dizziness.
- shortness of breath.
- palpitations (feeling that your heart is racing)
- skin irritations, such as a rash.
- possible kidney problems or increased potassium levels (these will be monitored by your health professional).
What is the difference between Zapril and cilazapril?
Cilazapril is used to treat high blood pressure and heart failure and to prevent kidney problems in people with diabetes. Find out how to take it safely and possible side effects. Cilazapril is also called Zapril.
Does cilazapril make you tired?
Drowsiness/reduced alertness: Cilazapril may cause drowsiness or dizziness, especially at the beginning of treatment or after a dose increase. This can affect your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how this medication affects you.
Does cilazapril cause cough?
There are many reports of a dry cough in patients treated with (ACE) inhibitors, but this is often considered a rare side effect. Eleven of 30 patients treated with the investigational ACE inhibitor cilazapril complained about a chronic cough.
What are the long term effects of taking felodipine?
If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks.
How long can you stay on ACE inhibitors?
There is therefore sufficient evidence to state that long-term ACE-inhibitor therapy for up to 5 years provides a continuous, cumulative benefit in patients with post-infarction heart failure or LV dysfunction.
Can I take ibuprofen with cilazapril?
Can you take other medicines? Some medicines available without a prescription may react with cilazapril including: anti-inflammatories, such as diclofenac (e.g. Voltaren®), ibuprofen (e.g. Nurofen®), or aspirin (e.g. Disprin®, in doses used for pain relief).
Can I drink alcohol with cilazapril?
You can take cilazapril with or without food. Limit alcohol intake while you are taking cilazapril. Alcohol can increase your chance of side effects such as dizziness and light-headedness.
Can felodipine affect eyes?
Check with your doctor right away if you have the following symptoms: blurred vision; confusion; severe dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; sweating; or unusual tiredness or weakness. This medicine may cause fluid retention (edema) in some patients.
What are the long term side effects of felodipine?
When is the best time of day to take felodipine?
Timing: Take felodipine once a day, at the same time each day. It is best taken in the morning. Swallow the whole tablet with a glass of water. Do not crush or chew the tablet.
Should ACE inhibitors be taken at night?
Many doctors recommend their patients take heart drugs in the morning with their breakfast, but a new study from Canada suggests that one group of drugs, angiotensin-converting enzyme (ACE) inhibitors, works best when taken at bedtime because they reduce the effect of a hormone that is most active during sleep.
What is Inhibace plus ® used to treat?
INHIBACE PLUS ® (cilazapril and hydrochlorothiazide) is indicated for the treatment of mild to moderate essential hypertension in patients for whom combination therapy is appropriate. In using INHIBACE PLUS ® consideration should be given to the risk of angioedema.
Are ACE inhibitors and dihydropyridine calcium channel blockers effective in high-risk patients?
However, results from the ACCOMPLISH trial suggest that the combination of an ACE inhibitor/ARB with a dihydropyridine calcium channel blocker, e.g. amlodipine or felodipine, is superior for reducing cardiovascular events in patients with a high CVD risk, compared with an ACE inhibitor/ARB-thiazide diuretic combination. 5
Is non-melanoma skin cancer a thiazide class effect?
There is currently insufficient evidence to determine if the increased risk of non-melanoma skin cancer is a thiazide class effect. If an alternative thiazide (or thiazide-like) diuretic is preferred, then indapamide, chlortalidone or bendroflumethiazide are potential options.
What are the alternatives to thiazide diuretics?
If an alternative thiazide (or thiazide-like) diuretic is preferred, then indapamide, chlortalidone or bendroflumethiazide are potential options.