Is 141 alkaline phosphatase high?
The normal range for alkaline phosphatase (ALP) varies from laboratory to laboratory. One common reference range is from 44 to 147 international units per liter (IU/L), but some organizations recommend a range of 30 to 120 IU/L.
What ALP level is considered high?
Values above 130 U/L are usually considered to be high. High levels of ALP in the blood may indicate bone, liver, or bile duct disease. ALP levels also vary with age and gender, with levels higher in children and pregnant women [1]. Higher ALP levels can occur in people with blood group B or blood group O [2].
What is ALP test range?
An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).
Is 147 alkaline phosphatase high?
The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (µkat/L). Normal values may vary slightly from laboratory to laboratory. They also can vary with age and sex. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women.
Is ALP a tumor marker?
Serum ALP was found to be a valuable tumor marker with high specificity in osteosarcoma.
What causes ALP to rise?
Causes of high ALP levels. ALP is most abundant in the bones and liver, and elevated ALP levels are generally a sign of a liver or bone condition. An obstruction of the liver or damage to it causes ALP levels to rise. Elevated levels can also result from an increase in bone cell activity.
What causes high ALP?
What medications cause high ALP?
Some examples of drugs that may cause a raised alkaline phosphatase include:
- Antibiotics: penicillin derivatives (1)
- Antiepileptic drugs: Carbamazepine.
- Antihistamines: Cetirizine (1)
- Cardiovascular drugs: Captopril (1)
- Disease modifying agents:
- Polycyclic aromatic hydrocarbons:
- Psychotropic drugs:
- Diabetes drugs:
Is 200 a high liver enzyme count?
In patients with uncomplicated alcoholic hepatitis, the AST value is rarely greater than 500 U per L and is usually no more than 200 to 300 U per L. The highest peak aminotransferase values are found in patients with acute ischemic or toxic liver injury.
What is mildly elevated ALP?
Nevertheless, in view of its benign nature, mildly elevated liver enzymes are usually due to inflammation, infection or metabolic disorder, rather than carcinoma. An isolated mild elevation of ALP level of less than five times the upper limit of normal (ULN) is not a common manifestation of liver malignancy (3).
Can stress cause high alkaline phosphatase?
Discussion. This study shows that ALP mRNA and activity were significantly increased by ER stress in human primary VSMCs in vitro.
What are symptoms of high alkaline phosphatase?
Why do I need an alkaline phosphatase test?
- Nausea and vomiting.
- Weight loss.
- Tiredness.
- Weakness.
- Jaundice, a condition that causes your skin and eyes to turn yellow.
- Swelling and/or pain in your abdomen.
- Dark-colored urine and/or light-colored stool.
- Frequent Itching.
What are normal ALP levels in blood?
Normal adult ALP levels range from 20 to 140 international units per liter of blood, or IU/L. ALP levels tend to soar during childhood when bones are growing and developing. So doctors don’t usually look at ALP levels when diagnosing problems in kids. How Do Doctors Perform an ALP Test? It’s a blood test.
How do I Check my ALP levels?
Eating can interfere with your ALP levels. Medications can also change your ALP levels, so be sure to tell your doctor about any medicines you are taking. How is the test administered? An ALP test requires a healthcare provider to draw a small sample of blood from your arm. This is done in your doctor’s office or in a clinical lab.
What does it mean when your ALP level is 140?
However, they may also indicate malnutrition, kidney cancer tumors, intestinal issues, a pancreas problem, or a serious infection. The normal range of ALP varies from person to person and depends on your age, blood type, gender, and whether you’re pregnant. The normal range for serum ALP level is 20 to 140 IU/L
What does it mean when your ALP is high?
The two main sources of ALP in your blood are the liver and bone. An ALP test is part of routine blood work. So doctors often find high ALPs by accident in someone who isn’t having any symptoms. Your doctor may also order an ALP test if she is worried about a liver, gallbladder, or bile duct disease.