Who manufactures Cerezyme?
Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is given intravenously after reconstitution as a treatment for Type 1 and Type 3 Gaucher’s disease.
When was Cerezyme FDA?
Since the approval of Cerezyme® (imiglucerase for injection) in May 1994, Genzyme has maintained a worldwide post-marketing database of spontaneously reported adverse events and adverse events discussed in the medical literature.
What is Alglucerase used for?
Alglucerase is used to treat Gaucher’s disease caused by the lack of a certain enzyme, glucocerebrosidase, in the body. This enzyme is necessary for your body to use fats.
Why is Cerezyme important?
Cerezyme has helped adults and children with Gaucher disease type 1 by improving key disease symptoms over the long term. As with any medicine, there may be potential side effects with Cerezyme. You should notify your doctor immediately if you experience any side effects while undergoing treatment with Cerezyme.
When was Cerezyme invented?
1994: The FDA approves Cerezyme® (imiglucerase), an ERT drug Genzyme developed as a successor to Ceredase.
How is VPRIV made?
VPRIV is made in a human cell line using Shire’s gene activation technology. The enzyme produced has the exact human amino acid sequence as that found in the naturally occurring human enzyme. VPRIV is used for the long-term treatment of patients with type 1 Gaucher disease.
How is vpriv made?
How much does elelyso cost?
The cost for Elelyso intravenous powder for injection 200 units is around $893 for a supply of 1 powder for injection, depending on the pharmacy you visit.
Who manufactures vpriv?
Velaglucerase alfa, sold under the brand name Vpriv and manufactured by Shire plc, is a hydrolytic lysosomal glucocerebroside-specific enzyme, which is a recombinant form of glucocerebrosidase indicated as a long-term enzyme replacement therapy for those with Gaucher disease Type 1.
Is vpriv made from human ovaries?
Currently, three approved ERTs exist for Gaucher disease, Sanofi’s Cerezyme, which is made from Chinese hamster ovary (CHO) cells, Pfizer’s Elelyso, which is made using carrot cells, and Vpriv by Shire (now Takeda), which is produced in a human fibroblast cell line.
What is VPRIV made from?
You may report side effects to FDA at 1-800-FDA-1088. The active ingredient of VPRIV is velaglucerase alfa, which is produced by gene activation technology in a human fibroblast cell line. Velaglucerase alfa is a glycoprotein of 497 amino acids; with a molecular weight of approximately 63 kDa.
What are enzyme infusions?
Enzyme replacement therapy (ERT) involves intravenous (IV) infusions to correct the underlying enzyme deficiency that causes symptoms of Gaucher disease (pronounced go-SHAY). In particular, a common use of enzyme replacement therapy is for lysosomal storage disease treatment.
Why does the body stop producing digestive enzymes?
There are several reasons why your body can’t produce enough enzymes on its own such as certain conditions like chronic pancreatitis, cystic fibrosis, and diabetes. Aging and lifestyle choices can gradually reduce your body’s ability to produce a sufficient amount of enzymes in the body.
What medication can replace Creon?
Zanpep, Viokace, Pancreaze, Pertzye, and Lactaid are some Creon alternatives.