Are terbinafine tablets safe?
For some infections, such as fungal nail infections, you may need to take terbinafine tablets for up to 3 months (sometimes longer). It is safe to take long-term if your doctor tells you to.
Is terbinafine still available?
The Food and Drug Administration (FDA) posted a discontinuation notice for Lamisil (terbinafine HCl; Novartis) tablets 250mg. The Company stated the permanent discontinuation was a business decision and is not due to manufacturing, product quality, safety, or efficacy concerns.
What is the risk of liver damage with terbinafine?
Clinically apparent liver injury from terbinafine occurs rarely (1 in 50,000 to 120,000 prescriptions), but many case reports and even case series have been described in the literature. Liver injury usually arises within the first 6 weeks of therapy.
Should I stop taking terbinafine?
Lamisil Tablets treatment should be discontinued. Advise patients to immediately report to their physician any symptoms of persistent nausea, anorexia, fatigue, vomiting, right upper abdominal pain, jaundice, dark urine, or pale stools. Lamisil Tablets treatment should be discontinued.
Is terbinafine hard on the liver?
As with most classes of drugs, terbinafine can potentially lead to liver problems. However, the data from the above suggests that oral terbinafine is safer than perhaps it is perceived, and minor side effects are far more likely for most patients than serious liver damage.
Can I buy oral terbinafine over-the-counter?
The topical versions of Lamisil (terbinafine) (cream, gel, and spray) are available over-the-counter, but Lamisil (terbinafine) tablets are available by prescription only.
How long can you take terbinafine?
The dose is usually 250 milligrams (mg) once a day for 6 weeks. Children 4 years of age and older and weighing over 35 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The dose is usually 250 mg once a day for 6 weeks.
How do I know if terbinafine is affecting my liver?
Despite its rarity, patients taking terbinafine who exhibit any of the symptoms of liver problems (nausea, vomiting, abdominal pain, fatigue, anorexia, general itching and dark urine) should urgently be referred for further assessment.
How many months can you take terbinafine?
You will usually take the tablets for anywhere from 6 weeks to 3 months. But, if you have a nail infection of the big toe or your nails grow very slowly, you may need to take the tablets for up to 6 months. It may take several months after you stop taking Lamisil tablets for your nail to look completely normal.
What should I avoid while taking terbinafine?
Avoid coffee, tea, cola, energy drinks or other sources of caffeine while taking terbinafine. Avoid exposure to sunlight or tanning beds. Terbinafine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Can terbinafine affect your heart?
Synopsis: The FDA has issued warnings about the potential for the development of liver failure and heart failure in patients receiving either itraconazole or terbinafine.
What can I take instead of terbinafine?
Itraconazole has higher clinical and mycological cure rates as compared to terbinafine. Although the cost of terbinafine is lower, the failure rate is higher and the duration of treatment required is longer. Therefore, itraconazole seems to be superior to terbinafine in the treatment of tinea corporis and tinea cruris.
Can I drink coffee on terbinafine?
Avoid caffeine (coffee, soda, chocolate) while you are using this medicine. Terbinafine may cause caffeine to stay in your body longer than usual.
How long do you need to take terbinafine?
What foods should I avoid while taking terbinafine?
If you will need two packets of oral granules with each dose, you may sprinkle the content of both packets on one spoonful or two spoonfuls of non-acidic food. Avoid caffeine (coffee, soda, chocolate) while you are using this medicine. Terbinafine may cause caffeine to stay in your body longer than usual.