Does the whooping cough have animal reservoirs?
Reservoir. Pertussis is a human disease. No animal or insect source or vector is known to exist. Adolescents, adults, and older school-age children are an important reservoir for B.
What are the virulence factors of Bordetella pertussis?
Some of these factors, including pertussis toxin (PT), adenylate cyclase, tracheal cytotoxin, dermonecrotic toxin, and lipopolysaccharide, exert a toxic effect. Other virulence factors, such as filamentous hemagglutinin (FHA), fimbriae, pertactin (Prn), and PT, have been reported to mediate the adherence of B.
What shape is Bordetella pertussis?
Bordetella pertussis is a small (approximately 0.8 μm by 0.4 μm), rod-shaped, coccoid, or ovoid Gram-negative bacterium that is encapsulated and does not produce spores.
What animal did whooping cough come from?
Bordetella pertussis does not naturally cause disease in animals. Nevertheless, experiments in animals have made important contributions to the present, although incomplete, understanding of pertussis. Mice, rats, rabbits, dogs, ferrets, and primates have been used. The respiratory colonization of mice by B.
Is Bordetella pertussis a virus or bacteria?
Pertussis is also known as whooping cough. It is a highly infectious bacterial disease involving the respiratory tract. It is caused by a bacterium (Bordetella pertussis or Bordetella parapertussis ) that is found in the mouth, nose and throat of an infected person.
What are the 3 stages of whooping cough?
There are three recognized stages of the disease: catarrhal, paroxysmal, and convalescent. The incubation period for Pertussis is 7 to 10 days.
Can humans get Bordetella?
Bordetella bronchiseptica in humans Humans can contract the Bordetella from other sources than dogs, and so it makes sense that humans can contract this bacterium from infected canines. However, to date, there is only circumstantial evidence that humans have ever contracted the bacterial infection from dogs.
How long does Bordetella pertussis live?
SURVIVAL OUTSIDE HOST: Survives for 3-5 days on inanimate dry surfaces 19. B. pertussis can also survive 5 days on clothes, 2 days on paper and 6 days on glass 20.