Does vasoconstriction of the afferent arteriole affect GFR?
Afferent arteriole constriction leads to decreased GFR and decreased RPF, resulting in no change in FF. One important function of prostaglandins is to dilate the afferent arteriole.
How does afferent arteriole affect GFR?
An increase in the afferent arteriolar diameter (decrease in resistance) causes an increase in the glomerular capillary hydrostatic pressure and an increase in GFR. A decrease in the diameter of the afferent arteriole has the opposite effect.
How does vasoconstriction affect GFR?
Vasodilation in the afferent arteriole and vasconstriction in the efferent arteriole will increase blood flow (and hydrostatic pressure) in the glomerulus and will increase GFR. Conversely, vasoconstriction in the afferent arteriole and vasodilation in the efferent arteriole will decrease GFR.
Why does vasoconstriction decrease GFR?
This vasoconstriction predominantly affects the afferent arteriole, effectively reducing hydrostatic pressure within the glomerular capillary lumen and decreasing glomerular filtration. The resulting reduction in the glomerular filtration rate (GFR) reduces the filtered load of Na+ to the nephrons. 2.
How does changing the afferent and efferent arteriole affect GFR?
A decrease in the diameter of the afferent arteriole has the opposite effect. An increase in the efferent arteriolar diameter (decrease in resistance) causes a decrease in the glomerular capillary hydrostatic pressure and a decrease in GFR. A decrease in the diameter of the efferent arteriole has the opposite effect.
What happens to GFR when the afferent arteriole dilates?
Dilation of the afferent arteriole has opposite effects. Constriction of the efferent arteriole alone also reduces RBF but with an increase in glomerular capillary pressure. This favors a relative increase in the GFR over the RBF, so that the filtration fraction is increased.
What happens when the afferent arteriole is constricted?
Constriction of the afferent arterioles has two effects: it increases the vascular resistance which reduces renal blood flow (RBF), and it decreases the pressure downstream from the constriction, which reduces the GFR.
What happens to GFR when the afferent arteriole dilates quizlet?
What happens if you dilate the afferent arteriole? The pressure in the glomerulus will increase because you’re allowing more of a volume of blood to get into the glomerulus, which creates a high pressure. Therefore, GFR increases due to the increased pressure.
Why does efferent arteriole constriction increased GFR?
Constriction of the efferent arterioles also increases the vascular resistance so it reduces RBF. The pressure within the glomerular capillaries may increase, however, because the flow is slowed by efferent arteriolar constriction.
What effect does increasing afferent arteriole diameter have on GFR and urine production explain your results?
An increase in efferent arteriole diameter will lead to a decrease in GFR and urine production because of the decrease in glomerular blood pressure.
What factors decrease GFR?
In this population-based study, we examined factors associated with glomerular filtration rates (GFR) in both genders. The findings of our study showed that obesity, diabetes, blood urea nitrogen, atherogenic factor, hypertension, meat consumption, and smoking were associated with lower GFR.
What causes the GFR to decrease?
Glomerular filtration rate is a measure of functional renal mass. Reductions in GFR can occur with primary renal disease, decreased renal perfusion, or obstructive renal disease.
What happens when afferent arterioles constrict?
What effect does increasing afferent arteriole diameter have on GFR and urine production?
An increase in afferent arteriole diameter will cause an increase in GFR and urine production.