How do you use Ace-031?
ACE-031 safety was evaluated through observation of the incidence and severity of adverse events. ACE-031 0.5 mg/kg subcutaneously once every 4 weeks for 12 weeks. ACE-031 1.0 mg/kg subcutaneously once every 2 weeks for 12 weeks.
What is ACE-031?
Introduction: ACE-031 is a fusion protein of activin receptor type IIB and IgG1-Fc, which binds myostatin and related ligands. It aims to disrupt the inhibitory effect on muscle development and provide potential therapy for myopathies like Duchenne muscular dystrophy (DMD).
What is myostatin blocker?
Myostatin is considered an inhibitor of satellite cell activation and as a result skeletal muscle hypertrophy. One promising supplement which has suppressed blood levels of myostatin by 44% is a proprietary bioactive ingredient, Myo-T12, which is follistatin derived from fertile chicken egg yolk isolate.
How does myostatin inhibit muscle growth?
Myostatin inhibits both myoblast cell proliferation and differentiation, reducing fiber number during muscle formation.
How do I take follistatin 344?
According to sites selling the drug over the internet, a subcutaneous injection of 100–200 mcg per day for a period of 10–20 days is recommended for 1 mg follistatin-344. Follistatin-344 inhibits myostatin, which is responsible for regulating and limiting muscle growth, leading to an increase in muscle mass [9].
What is the strongest myostatin inhibitor?
YK-11 is one of the strongest myostatin inhibitors currently available.
Are there any real myostatin inhibitors?
Stamulumab (Myo-29), developed by Wyeth Pharmaceuticals (now Pfizer), is the first myostatin inhibitor to progress to clinical trials.
Are myostatin inhibitors illegal?
Myostatin inhibitors are specifically banned by the World Anti-Doping Agency (WADA).
How much follistatin should I take?
The typical daily dosage among these users is 100 to 300 micrograms, injected directly into the specific muscles the user would like to boost. Many commenters on bodybuilding forums have claimed not to have found any significant effects on muscle growth after injecting follistatin.
What is follistatin 344 used for?
Follistatin-344 is a recombinant human follistatin containing 344 amino acids that block myostatin and increase muscle mass. Preclinical and phase studies are in progress, as this peptide is a promising research peptide for the treatment of muscle diseases involving muscle atrophy [9, 21, 22].
How strong is YK-11?
Yk11 study shows the clinical dosage of this compound should be between 10-15 mg in two divided doses. There has been no data available for knowing the safe and effective dose of YK-11 since no human trial data have been gathered on this one. Bodybuilders who use YK-11 use it in 5-30mg doses for a 4-8 weeks cycle.
Does YK-11 lower myostatin?
As a myostatin inhibitor, YK-11 helps to reduce muscle myostatin protein effectively, leading the body to a dramatic increase in muscle mass.
What myostatin inhibitors do bodybuilders use?
Myostatin Inhibitor Stacking Options with other SARMs
- MK-2866 (Ostarine)– which is a potent SARM that helps to build muscle and burn fat.
- LGD-4033 (Ligandrol)– which is another powerful SARM that is great for building muscle mass and strength.
- S4 (Andarine)– which is SARM that helps to burn fat and maintain muscle mass.