What does it mean to be heterozygous for MTHFR C677T?
In people who are heterozygous for an MTHFR C677T mutation, there is reduced enzyme function—≈65% of normal. In people who are homozygous for MTHFR C677T, there is only 30% of normal enzyme function.
What is the best supplement for MTHFR mutation?
Supplement with essential nutrients Methyl-B12, methyl-folate, TMG, N-acetylcysteine, riboflavin, curcumin, fish oil, Vitamins C, D, E, and probiotics are excellent supplements your body will love more so if you have an MTHFR mutation.
How is MTHFR C677T treated?
What are the treatment options for patients with the MTHFR C677T mutation? Summary: Patients with the MTHFR C677T mutation have a reduced ability to convert folic acid into its active form, L-methylfolate. Both L-methylfolate and folic acid are possible treatment options for these patients.
How common is MTHFR C677T mutation?
There are two common types, or variants, of MTHFR mutations: C677T and A1298C. These gene mutations are relatively common. In fact, in the United States, around 25% of people of Hispanic descent and 10–15% of people of Caucasian descent have two copies of C677T.
What does C677T mutation mean?
Two copies of the MTHFR C677T mutation can result in the following symptoms: Decreased enzyme activity levels. Elevated homocysteine levels, especially with concurrent deficiency of vitamins B12, B6 (pyridoxine), or folic acid. 3-fold increased risk for premature cardiovascular disease.
What is the MTHFR gene?
MTHFR specifically is a gene that holds the recipe for methylenetetrahydrofolate reductase – an enzyme that helps our bodies convert vitamin B9 (also known as folate) into a usable form called methylfolate. This process is called methylation. Now, if you’re thinking, “ Oh, no problem!
Who is the mommypotamus?
I’m Heather, aka The Mommypotamus. I’m a wife, mom, real food lover, research geek, and amateur homesteader. And potamus… obviously. MORE ABOUT HEATHER | WHAT IS A MOMMYPOTAMUS?
Is folic acid safe for MTHFR mutations?
Unfortunately, folic acid – which is a synthetic vitamin found in fortified foods and almost all vitamin supplements – is considered harmful for people with MTHFR mutations. Though it is easily absorbed by the body, people who have low levels of the MTHFR enzyme are not able to convert very much of it into usable form.
How can I support my MTHFR mutation?
I recommend that those with MTHFR mutations symtoms do so as well. When you support your methylation and detox pathways by following a MTHFR detoc protocol, you can support your MTHFR mutation and overcome the hurdles of MTHFR mutation symptoms!