What is phenothiazine used for?
Descriptions. Phenothiazines are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. Some are used also to control agitation in certain patients, severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients.
Which antihistamine is of phenothiazine class?
ANTIHISTAMINES, PHENOTHIAZINE-DERIVATIVE (Systemic) Another commonly used name for trimeprazine is alimemazine .
Is phenothiazine a dopamine antagonist?
Phenothiazine and metoclopramide, both neuroleptics, are dopamine antagonists that have varying degrees of activity on the serotonergic, histaminic, adrenergic, and cholinergic neurotransmitter systems.
What is the pharmacology of phenothiazine?
The phenothiazines are a group of chemical agents with neuroleptic, antiemetic, antihistaminic, anticholinergic and sedative activities. Their main pharmacological response is determined by variations in the chemical structure of the side-chain at position 10 of the phenothiazine ring.
Which drugs are phenothiazine?
Examples of phenothiazines include: chlorpromazine (brand name: Thorazine), fluphenazine (Duraclon), mesoridazine (Serentil), perphenazine (Etrafon and Trilafon), prochlorperazine (Compazine), promazine (Robinul and Anectine), thioridazine (Mellaril), trifluoperazine (Stelazine) and triflupromazine (Robinul).
Is Trifluoperazine a phenothiazine?
Trifluoperazine is a phenothiazine used to treat depression, anxiety, and agitation. A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Which drugs are dopamine antagonists?
Dopamine Antagonists Dopamine antagonists are a class of drugs that bind to and block dopamine receptors….Dopamine antagonist drugs include:
- Thorazine or Largactil (chlorpromazine)
- Reglan (metoclopramide)
- Phenergan (promethazine)
- Invenga (paliperidone)
- Risperdal (risperidone)
- Seroquel (quetiapine)
- Clozaril (clozepine)
Which drugs are phenothiazines?
What drugs have phenothiazines?
What class of drugs is trifluoperazine?
Trifluoperazine is in a group of medications called conventional antipsychotics.
What are dopamine agonist drugs?
Dopamine agonists are a broad category of medications that mimic the actions of dopamine in the body to relieve symptoms related to low levels of dopamine. They’re most often used to treat Parkinson’s disease and restless legs syndrome but are also prescribed for other conditions.
What are serotonin dopamine antagonists?
Relatively potent antagonism of serotonin 5-HT2A receptors coupled with relatively weaker antagonism of dopamine D2 receptors is the central pharmacological characteristic shared by most SGAs. This profile continues to be a favored model for developing new SGAs, commonly defined as serotonin/dopamine antagonists.
What type of phenothiazine is trifluoperazine?
Trifluoperazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders.
What is trifluoperazine side effects?
Trifluoperazine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- dizziness, feeling unsteady, or having trouble keeping your balance.
- blurred vision.
- dry mouth.
- stuffed nose.
- nausea.
- difficulty urinating.