What is the medication carboplatin used for?
Descriptions. Carboplatin belongs to the group of medicines known as alkylating agents. It is used to treat cancer of the ovaries. It may also be used to treat other kinds of cancer, as determined by your doctor.
Is carboplatin a chemotherapy or immunotherapy?
Paclitaxel and carboplatin are chemotherapy drugs used as part of the usual treatment approach for this type of cancer. This study aims to assess if adding immunotherapy to these drugs is better or worse than the usual approach for treatment of this cancer.
Is carboplatin a chemo drug?
Carboplatin is a chemotherapy treatment for many different types of cancer. You can have carboplatin by itself or in combination with other chemotherapy drugs depending on the type of cancer you have.
What cancers is carboplatin used for?
Carboplatin is a chemotherapy drug. It is used to treat ovarian and lung cancer.
What kind of chemo is carboplatin?
Drug type: Carboplatin is an anticancer drug (“antineoplastic” or “cytotoxic”) chemotherapy drug. Carboplatin is classified as an “alkylating agent.”
What is the most common side effect of carboplatin?
Stomach pain, body aches/pain, diarrhea, constipation, weakness, nausea, and vomiting may occur. Nausea and vomiting can be severe in some patients but usually go away within 24 hours of treatment.
What are the common side effects of carboplatin?
Carboplatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea.
- vomiting.
- diarrhea.
- constipation.
- sores in the mouth and throat.
- pain, burning, or tingling in the hands or feet.
How long does it take to recover from carboplatin?
This means that you have the drug and then a rest to allow your body to recover. Each cycle usually lasts 3 weeks (21 days). Depending on your cancer type you might have up to 8 cycles which can take up to about 6 months.
What is the target AUC for carboplatin INJ?
Background Info. Previously treated patients: a target AUC of 4-6 mg/mL•min using single agent Carboplatin Inj appears to provide the most appropriate dose range. For patients who previously DID NOT receive chemotherapy (untreated), a target AUC of 7 (range: 6-8) mg/mL per minute has been recommended when carboplatin is used alone.
What is the difference between carboplatin dosing according to BSA and AUC?
5) AUC-based carboplatin dosing is more accurate than dosing according to BSA. 6) Several factors must be considered in addition to the GFR to determine the precise dosage. Additional factors that should be assessed include: previous exposure to chemotherapy or radiotherapy, and overall health status.
What is the maximum carboplatin dose for AUC and GFR?
A Calvert formula-calculated carboplatin dose, based on estimated GFR using IDMS serum creatinine, could be higher than desired and result in increased toxicity. To avoid toxicity, FDA recommends capping the carboplatin dose for a desired AUC. The maximum dose is based on a capped GFR estimate at 125 mL/min for patients with normal renal function:
How is carboplatin dosing calculated?
This carboplatin dosing calculator uses the Calvert method to calculate the total carboplatin dose needed to achieve a given AUC (area under the free carboplatin plasma concentration versus time curve) while taking into account renal function. Please note that dose is provided in mg not mg/m 2.